Dados do Trabalho

Título

Clinical Profile Comparisons in Short versus Long Sleepers in the ELSA-Brasil Study

Introdução

Growing evidence in the literature suggest that not only short (SSD) but also long sleep duration (LSD) are associated with poor prognosis in several clinical domains. However, whether the risk attributed to the short and long sleep durations are driven for similar factors is unknown

Objetivo

Compare the characteristics of short and long sleepers

Métodos

This is a large cross-sectional investigation from the ELSA-Brasil study. Each participant was submitted to a standard interview and physical examination. The sleep duration was measured by using an Actiwatch model 2(Philips Respironics)over a period of 7 consecutive nights during a typical week.SSD and LSD were defined by <6 and >8 hours, respectively.Otherwise, the participants were considered in the reference group (6-7.99h).To evaluate the clinical profile of these groups,we performed anthropometric and blood pressure measurements, evaluation of several comorbidities(including objective measurements of obstructive sleep apnea,OSA)and laboratory exams(including glucose,lipid profile and markers of inflammation)

Resultados

A total of 2,063 participants were included in the final analysis(age 49±8 years;42.8% men; 30% with OSA).SSD was observed in 26.9% and LSD in 6.5% of the participants. Compared to the reference group (n=1375; 66.7%), the participants with SSD had higher frequency of married status (66.1 vs. 74%), Blacks (10.6 vs.17.9%) and levels of triglycerides (108vs.119 mg/dL); lower frequency of the following variables: women (61.7 vs. 44%), Whites (64.6vs.52.2 %),high-degree education (51.7vs.44%),monthly per capita income (R$1.740,30vs1.424,06)and levels of HDL cholesterol (55vs.52 mg/dL). Regarding sleep variables, SSD was associated with higher frequency of OSA (41.9vs.29.7%)and excessive daytime sleepiness (46.2 vs. 36.3%), AHI [12.1 (4.9–23.8)vs.9.3(4.3–17.7)ev/h], time SpO2<90% (0.7vs.0.3%), lower lowest SpO2 (85 [83-90%]vs.87 [81-89])when compared with the reference group. In contrast, the participants with LSD were older (51±9vs.49±8 years), had higher frequency of depressive symptoms (9vs.3.6%), sleep latency (27.3±19.5vs.22.1±16.7 minutes),number of awakenings(52.2±21.2vs. 44.7±18)and wake after sleep onset(38.1±11.6vs.34±11.1 minutes)as compared to the reference group(p<0.05)

Conclusões

While short sleepers presented higher frequency of OSA, excessive daytime sleepiness, as well as ethnic and socioeconomical factors, long sleepers were older and had a higher percentage of depressive symptoms and sleep fragmentation

Palavras-chave

sleep duration

Área

Área Clínica