Dados do Trabalho

Título

Relationship of sleep duration, quality and metabolic parameters in women with severe obesity

Introdução

Sleep has an important role in maintaining health. Short sleep duration and poor sleep quality have been increasingly recognized as factors that influence metabolism and endocrine dysfunction, increasing the risk of cardiovascular disease. In individuals with obesity, both the quality and duration of sleep may be impaired.

Objetivo

To evaluate the quality and duration of sleep in women with severe obesity and to relate it to metabolic parameters.

Métodos

This is a cross-sectional study with women with a body mass index (BMI) greater than or equal to 40 kg/m² who will undergo bariatric surgery. Weight, height, hip (HC) and waist (WC) circumferences were measured and blood samples were collected to assess the glycemic and lipid profiles. Homa-IR and Homa-β values were calculated and systolic (SBP) and diastolic (DBP) blood pressure values were collected from medical records. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) and they were classified as good sleep quality (<5) and poor sleep quality (≥5). The variables were analyzed for normality using the Shapiro-Wilk test. For comparison of the mean between the groups, the univariate GLM was used and the Pearson and Spearman correlations were performed.

Resultados

A total of 39 women were enrolled in this study. The mean age was 40.21 ± 8.68 years, with mean BMI of 48.65 ± 7.19 kg/m², PQSI score of 8.15±5.47 and sleep duration of 7.09 ± 1.09 h. In the total sample, a correlation was observed between sleep duration and HbA1c (p=0.021 rho= -0.368). It was observed that 71.79% (n=28) of the volunteers had poor sleep quality. In the low-quality sleep group, it was observed a higher mean WC (p=0.035) and correlations of sleep duration with glucose (p=0.024 rho=- 0.427) and Homa- β (p=0.037 rho=0.396).

Conclusões

Women with severe obesity have high prevalence of poor sleep quality. Data suggest that poor sleep quality may be factors that influence metabolic parameters, such as glycemic control and waist circumference.
CNPq Edital n°434159/2018-2 ; FUNAPE: nº01/2022

Palavras -chave

obesity, sleep, PQSI, glycemic profile